Folium Biosciences
About Folium Biosciences

Folium Biosciences is a global leader in CBD suppliers

Phytocannabinoid-Rich (PCR) hemp oil
CBD Medica ™ high phytocannabinoid PCR hemp oil is made from Folium Biosciences, Colorado, USA.
FB is one of the largest manufacturers of raw materials and products for CBD in the world, and has more than 3 facilities in the world.
We supply CBD raw materials and products to many of the world's leading manufacturers, with 2000 hectares (20 square kilometers) of agricultural land and approximately 27900 square meters of indoor production space.
In addition, it has nearly 200 patents, and the seeds are original and suitable for manufacturing CBD products.
As of March 2021, FB has received hemp products from the Colorado Department of Public Health and Environment (CDPHE).
It is the first company in the world to receive approval for unlimited sales and manufacturing and sales of processed foods.
With these approvals, we are confident in delivering Phytocannabinoid-Rich hemp oil CBD oils and related dissolving technologies and health foods to our customers as an industry-leading hemp product manufacturer. FB legally manufactures CBD-containing health foods with a license to manufacture and sell processed foods for CBD products.
The Colorado government has rigorously inspected Folium Biosciences' manufacturing facilities, approved unlimited sales of hemp products, and certified 0.0% THC for the following products:
- Soft gel
- Tablets / capsules
- Tincture
- Supplement
- Beverage
- Oil products: THC below the detection limit
- HydroPCR
- Water-soluble powder and liquid products
- Below the THC detection limit (test result: 0% THC), phytocannabinoid CBD oil and the final product, Folium Biosciences, have passed the Colorado Government inspection on a 100-point scale.In addition to Colorado's food and cosmetics licenses, we have obtained the following licenses through our subsidiaries and affiliated companies.・ GPP (Good Pharmaceutical Practice) Certification Principles for high quality pharmaceutical medicine ・ API (Active Pharmaceutical Ingredient) License ・ Pharmaceutical Manufacturing License ・ EU Pharmaceutical Manufacturing License
- Kosher Halal Certification
- ISO certified clean room (manufacturing and R & D facility: Pueblo, Colorado, USA)
- The extraction and purification facility has also been approved by the FDA (US Food and Drug Administration) (acquisition year: 2018).
Folium Biosciences not only meets all food safety standards, but also aims to meet the FDA's pharmaceutical manufacturing standards.
Vertical Integration
Vertical integration system
Products made by Folium Biosciences use our unique technology to develop seeds of high phytocannabinoid species and cultivate them on our own farmland.
It is possible to provide a stable supply of high-level products by centrally managing all the manufacturing of products by one company.
This is called vertical integration.

- Achieve a global competitive advantage in the hemp-derived phytocannabinoid industry with unique varieties
- We do not use genetically modified varieties.
- Realization of high cannabidiol (CBD) / low THC with proprietary varieties
- Phytocannabinoid-Rich and high terpenoid varieties harvest
- Phytocannabinoid-Rich varieties
- Completely in-house growth
- Outdoor cultivation
- High CBD extraction and purification
- Chromatographic tests and lot tests by a third-party laboratory confirm accurate quantification of phytocannabinoids and complete elimination of THC in all steps
- Realization of Broad Spectrum: Contains more than 40 natural terpene components such as unpsychotropic phytocannabinoids and cannabigerol (CBG), cannabinol (CBN), cannabichromene (CBC)
- The result is the purification of high phytocannabinoid hemp oil with the highest quality broad spectrum, as well as the complete elimination, manufacture and development of solvents, heavy metals, pesticides and THC.
- In-house product development team
- Unique manufacturing method
- Strict stability test
Comprehensive implementation by a single company from manufacturing to inspection and bottling enables quick response and resolution of various problems.

Safe natural material
Folium Biosciences Broad Spectrum Phytocannabinoid-Rich hemp oil (PCR) varieties are produced in the United States by natural organic farming. FB maintains the reproducibility of varieties with the latest cloning technology and provides safe and distinctive products.
We ensure transparency throughout the entire supply chain.
Extraction
- Use of high quality ethanol and supercritical CO2
- Extraction of high quality extracts with high CBD, no THC, and high terpene varieties
- Additive-free
- Maintenance of terpenes and other volatile components by closure / low temperature process
purification
- Exclude THC below the detection limit (0%)
- Preservation of other cannabinoids, terpenes, and flavonoids
- Elimination of detectable solvents
- Compliance with legal requirements for heavy metals
- Compliance with legal requirements for pesticides
Unique process
Folium BiosciencesPhytocannabinoid-Rich (PCR) hemp oil is produced using a unique process.We also extract cannabinoids, terpenes, and fatty acids from natural plants in a broad spectrum.Furthermore, the closure / low temperature process is used to prevent the decomposition of molecules during the extraction / purification process.


Feature
- Mass production of Phytocannabinoid-Rich(PCR) hemp oil using state-of-the-art production facilities.
- After conducting an in-house inspection, the inspection result is verified by a third-party inspection organization using appropriate HPLC equipment (High-performance liquid chromatography).
- Ensuring transparency to customers by applying Good Manufacturing Practices (GMP) through the supply chain.
- The industry's most advanced extraction and refining equipment is independently produced in Amsterdam to realize further vertical integration (production control in all processes from seed production to sales of finished products).
Inspection agency and contents
Folium Biosciences Broad Spectrum /Phytocannabinoid-Rich (PCR) hemp products are tested by a third party laboratory in the United States.Strict inspection is essential to achieve the highest quality in the industry.As a result, we have achieved complete elimination of solvents and compliance with heavy metal and pesticide regulations.These inspections are carried out by a third-party inspection organization and use effective and necessary methods in accordance with our quality standards.
Legal compliance and licensing
Folium BiosciencesCompanyIs the first company in the world to receive unlimited sales of hemp products and the manufacture and sale of processed foods from the Colorado Department of Public Health and Environment (CDPHE) as of January 2021.

With these approvals, we are confident in delivering Phytocannabinoid-Rich hemp oil CBD oils and related dissolving technologies and health foods to our customers as an industry-leading hemp product manufacturer. FB legally manufactures CBD-containing health foods with a license to manufacture and sell processed foods for CBD products.
The Colorado government has rigorously inspected Folium Biosciences' manufacturing facilities, approved unlimited sales of hemp products, and certified 0.0% THC for the following products:
Folium Biosciences not only meets all food safety standards, but also aims to meet the FDA's pharmaceutical manufacturing standards.
* This product is not a drug.It is not intended for specific treatment or prevention.